https://ogma.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:54219 ACTA2), collagen (COL) 1A1 and fibulin-1 (Fbln1) and higher Fbln1 protein deposition after 7 days. Our results show that exposure of lung fibroblasts to fibrotic stiffness activates genes and secreted factors that are part of fibrotic responses and part of the Senescence-associated secretory phenotype (SASP). This overlap may contribute to the creation of a feedback loop whereby fibroblasts create a perpetuating cycle reinforcing progression of a fibrotic response.]]> Tue 13 Feb 2024 11:58:49 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:33143 −26) and a 1.4 fold in the severe COPD -related genes (P = 2.3 × 10⁻¹²). There was no significant enrichment of the mice and human smoking-related genes in mild COPD signature. These data suggest that murine smoke models are strongly representative of molecular processes of human smoking but less of COPD.]]> Tue 03 Sep 2019 18:18:55 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:48871 Thu 13 Apr 2023 12:47:57 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:14805 Fri 02 Nov 2018 14:20:43 AEDT ]]>